(S)-Bicalutamide-d4 ity C hydrochloride selective and cell-permeable p300 histone

selective and cell-permeable p300 histone acetyltransferase (HAT) inhibitor with IC50 of 5 μM

prevents its degradation

Acetyl-CoA is the primary substrate for the tricarboxylic acid cycle in mitochondria and modulates the reserves of free CoA which is essential to the function of the tricarboxylic acid cycle

88(12):1971-8

for 3 months) treatment significantly delays the progression of glomerulonephritis and increases the survival rate of NZB/W F1 mice

(S)-Bicalutamide-d4 ity C hydrochloride selective and cell-permeable p300 histoneProduct information CAS Number: 1217769 79 3 Molecular Weight: 434. 40 Formula: C18H14F4N2O4S Chemical Name: (2S) N [4 cyano 3 (trifluoromethyl)phenyl] 3 [4 fluoro(2,3,5,6 H)benzenesulfonyl] 2 hydroxy 2 methylpropanamide Smiles: [2H]C1=C(C([2H])=C([2H])C(F)=C1[2H])S(=O)(=O)C[C@@](C)(O)C(=O)NC1=CC(=C(C=C1)C#N)C(F)(F)F InChiKey: LKJPYSCBVHEWIU YNWMVSOESA N InChi: InChI=1S C18H14F4N2O4S c1 17(26,10 29(27,28)14 6 3 12(19)4 7 14)16(25)24 13 5 2 11(9