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SKI-178 Size:10mg solid CAS Number: 356559-13-2

SKU: 8407927841

4.3
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Description

CAS Number: 356559-13-2

Development of a comprehensive set of P2 receptor pharmacological research compounds

CYP17 inhibition is a new strategy to prevent androgen synthesis and treat lethal metastatic prostate cancer

H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14

also known as XRP0673

SKI-178 Size:10mg solid CAS Number: 356559-13-2SKI 178 is a potent sphingosine kinase 1 (SphK1) and SphK2 inhibitor. SKI 178 is cytotoxic at IC50 concentrations ranging from 1. 8 to 0. 1 M in both drug sensitive and multi drug resistant cancer cell lines (i. e., MTR3, NCI ADR and HL60 VCR cells). SKI 178 induces apoptosis in a CDK1 dependent manner in human acute myeloid leukemia cell lines. Product information CAS Number: 1259484 97 3 Molecular Weight: 394. 42 Formula: C21H22N4O4 Chemical Name:

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