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12, 14-Dichlorodehydroabietic acid Catalog No.:M14094-2 GDC-0941 was used at 1-10

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Description

GDC-0941 was used at 1-10 µM in vitro and in cellular assays

PF-03084014

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12, 14-Dichlorodehydroabietic acid Catalog No.:M14094-2 GDC-0941 was used at 1-1012,14 Dichlorodehydroabietic acid, a chlorinated resin acid, is a potent Ca2+ activated K+ (BK) channel opener. 12,14 Dichlorodehydroabietic acid blocks GABA dependent chloride entry in mammalian brain and operates as a non competitive GABAA antagonist. 12,14 Dichlorodehydroabietic acid increases cytosolic free Ca2+ and stimulates transmitter release. Product information CAS Number: 65281 77 8 Molecular Weight: 369. 33 Formula: C20H26Cl2O2 Chemical

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