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which indicates that Plk4 also controls centriole amplification in differentiated cells
000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites
2014 Dec 2
CPI-613 was known to strongly disrupt tumor mitochondrial metabolism
5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea
DBM 1285 dihydrochloride 311727 which indicates that Plk4 alsoProduct information Molecular Weight: 468. 42 Formula: C21H24Cl2FN5S Chemical Name: N cyclopropyl 4 [4 (4 fluorophenyl) 2 (piperidin 4 yl) 1,3 thiazol 5 yl]pyrimidin 2 amine dihydrochloride Smiles: Cl. Cl. FC1C=CC(=CC=1)C1N=C(SC=1C1C=CN=C(NC2CC2)N=1)C1CCNCC1 InChiKey: ANQWETXPBPZVOF UHFFFAOYSA N InChi: InChI=1S C21H22FN5S. 2ClH c22 15 3 1 13(2 4 15)18 19(28 20(27 18)14 7 10 23 11 8 14)17 9 12 24 21(26 17)25 16 5 6 16;; h1 4,9,12,14,16,23H,5 8,10