1, 2-Bis(2-iodoethoxy)ethane Catalog No.:M14690-2 InChi: InChI=1S/C25H27N5O5/c1-4-20(10-11-26)35-25(32)28-16(2)17-6-5-7-18(12-17)29-24(31)30-19-8-9-21(22(13-19)33-3)23-14-27-15-34-23/h5-9

InChi: InChI=1S/C25H27N5O5/c1-4-20(10-11-26)35-25(32)28-16(2)17-6-5-7-18(12-17)29-24(31)30-19-8-9-21(22(13-19)33-3)23-14-27-15-34-23/h5-9

has an IC50 of <1 μM

MS417 effectively blocks BRD4 binding to NF-κB

RO4917838 (R)

followed by a surge of apoptosis

1, 2-Bis(2-iodoethoxy)ethane Catalog No.:M14690-2 InChi: InChI=1S/C25H27N5O5/c1-4-20(10-11-26)35-25(32)28-16(2)17-6-5-7-18(12-17)29-24(31)30-19-8-9-21(22(13-19)33-3)23-14-27-15-34-23/h5-91,2 Bis(2 iodoethoxy)ethane is a PEG based PROTAC linker. 1,2 Bis(2 iodoethoxy)ethane can be used in the synthesis of MT802 (HY 122562) and SJF620 (HY 133137). MT 802 and SJF620 are potent PROTAC BTK degraders with DC50s of 1 nM and 7. 9 nM, respectively. Product information CAS Number: 36839 55 1 Molecular Weight: 369. 97 Formula: C6H12I2O2 Chemical Name: 1 iodo 2 [2 (2 iodoethoxy)ethoxy]ethane Smiles: ICCOCCOCCI InChiKey: BCAGFJXMCZSAHD UHFFFAOYSA N