Linerixibat tiglinide Calcium 13(21)12(8)20)15(3)5-10(19)14(24-11)17(15)7-23-17/h4

13(21)12(8)20)15(3)5-10(19)14(24-11)17(15)7-23-17/h4

2017 Sep 22

and dog plasma

Smiles: COC1C2OC(=O)C3C=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(OC)=C4OC(=O)C(=CC=1O)C=2C4=3

Smiles: CC(C)(C)C[C@@H]1N[C@H]([C@H](C2=CC=CC(Cl)=C2F)[C@@]1(C#N)C1=CC=C(Cl)C=C1F)C(=O)NC1=CC=C(C=C1OC)C(O)=O

Linerixibat tiglinide Calcium 13(21)12(8)20)15(3)5-10(19)14(24-11)17(15)7-23-17/h4Linerixibat (GSK2330672) is a highly potent, nonabsorbable and orally active apical sodium dependent bile acid transporter (ASBT) inhibitor with an IC50 of 42 nM human ASBT. Linerixibat can be used as lipid lowering agent. Linerixibat has the potential for type 2 diabetes and Primary Biliary Cholangitis treatment. Product information CAS Number: 1345982 69 5 Molecular Weight: 546. 68 Formula: C28H38N2O7S Chemical Name: 3 ({[(3R,5R) 3 butyl 3 ethyl 7