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CYP11B2-IN-1 17695 3-dien-1-yl]-11-oxo-10-oxatricyclo[6

SKU: 87861314983

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Description

3-dien-1-yl]-11-oxo-10-oxatricyclo[6

CAS Number: 2050524-24-6

InChi: InChI=1S/C8H15NO6/c1-4(12)9-5(2-10)7(14)8(15)6(13)3-11/h2

K02288 binds to ALK1 in an ATP-mimetic fashion with two hydrogen bonds to the kinase hinge

PubMed PMID: 27283322

CYP11B2-IN-1 17695 3-dien-1-yl]-11-oxo-10-oxatricyclo[6CYP11B2 IN 1 is a CYP11B2 inhibitor with an IC50 of 2. 3 nM. CYP11B2 IN 1 inhibits CYP11B1 with an IC50 of 142 nM. Product information CAS Number: 1356479 78 1 Molecular Weight: 311. 35 Formula: C18H18FN3O Chemical Name: 2 [5 (1 cyclopropyl 6 fluoro 1H 1,3 benzodiazol 2 yl)pyridin 3 yl]propan 2 ol Smiles: CC(C)(O)C1=CN=CC(=C1)C1=NC2=CC=C(F)C=C2N1C1CC1 InChiKey: OAMLIJKKGZLNHE UHFFFAOYSA N InChi: InChI=1S C18H18FN3O c1 18(2,23)12 7 11(9 20 10 12)17 21

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