MS 39 BSK805 Smiles: CC1=CC(=CC=C1NC1=NC(=CC=N1)C1=CN=CC=C1)NC(=O)C1=CC(=CC=C1)NC(=O)/C=C/CN(C)C

Smiles: CC1=CC(=CC=C1NC1=NC(=CC=N1)C1=CN=CC=C1)NC(=O)C1=CC(=CC=C1)NC(=O)/C=C/CN(C)C

Ketanserin significantly prolongs action potential duration (APD) at 50% repolarization by 218% and APD at 90% repolarization by 256% with no significant effect on other action potential parameters in rat ventricular myocytes

2014 Jul 23

LT-253) inhibits c-Myc expression and selectively induces CDKN1A (p21)

2014 Nov 26

MS 39 BSK805 Smiles: CC1=CC(=CC=C1NC1=NC(=CC=N1)C1=CN=CC=C1)NC(=O)C1=CC(=CC=C1)NC(=O)/C=C/CN(C)CMS39 is a novel E3 ligase von Hippel Lindau recruiting EGFR degrader. Product information Molecular Weight: 1056. 72 Formula: C55H71ClFN9O7S Chemical Name: (2S,4R) 1 ((S) 2 (11 (4 (3 ((4 ((3 chloro 4 fluorophenyl)amino) 7 methoxyquinazolin 6 yl)oxy)propyl)piperazin 1 yl) 11 oxoundecanamido) 3,3 dimethylbutanoyl) 4 hydroxy N (4 (4 methylthiazol 5 yl)benzyl)pyrrolidine 2 carboxamide Smiles: