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JZP-430 Catalog No.:M28553-C Chemical Name: (2S)-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2R)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanediamide

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Description

Chemical Name: (2S)-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2R)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanediamide

Formula: C10H8N4O2

RV521 exhibited a mean IC50 of 1

Smiles: CCOC(=O)C1C=C2NC3[C@@H]4OC5=C6C(C[C@H]7N(CC8CC8)CC[C@]64[C@@]7(O)CC=3C2=CC=1)=CC=C5O

Smiles: CC(C)(O)[C@@H](O)CC[C@@H](C)[C@H]1CC[C@H]2/C(/CCC[C@@]21C)=C/C=C1/C[C@@H](O)CCC/1=C

JZP-430 Catalog No.:M28553-C Chemical Name: (2S)-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2R)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanediamideJZP 430 is a potent, highly selective, irreversible inhibitor of hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230 fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL). Product information CAS Number: 1672691 74 5 Molecular Weight: 354. 47 Formula: C16H26N4O3S Chemical Name: 4 (morpholin 4 yl) 1,2,5 thiadiazol 3 yl N cyclooctyl N methylcarbamate Smiles: CN(C1CCCCCCC1)C(=O)OC1=NSN=C1N1CCOCC1 InChiKey:

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