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BMS-626529 Size:Solid 2 mg Smiles: OC1(CN(C1)C(=O)C1=CC=C(F)C(F)=C1NC1=CC=C(I)C=C1F)[C@H]1CCCCN1

SKU: 89821707408

4.4
USD120.00 USD140.00

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Description

Smiles: OC1(CN(C1)C(=O)C1=CC=C(F)C(F)=C1NC1=CC=C(I)C=C1F)[C@H]1CCCCN1

PMCID: PMC5469273

acetylcholine

InChiKey: VVIAGPKUTFNRDU-ABLWVSNPSA-N

InChi: InChI=1S/C20H13NO5/c22-20-12-5-10-2-4-15-19(26-9-24-15)18(10)17(13(12)7-21-20)11-1-3-14-16(6-11)25-8-23-14/h1-6H

BMS-626529 Size:Solid 2 mg Smiles: OC1(CN(C1)C(=O)C1=CC=C(F)C(F)=C1NC1=CC=C(I)C=C1F)[C@H]1CCCCN1Temsavir, also known as BMS 626529, is a potent HIV 1 attachment inhibitor. BMS 663068 is also the phosphonooxymethyl prodrug of BMS 626529 that targets HIV 1 gp120 and prevents its binding to CD4(+) T cells. BMS 626529 had half maximal effective concentration (EC(50)) values of <10 nM against the vast majority of viral isolates; however, susceptibility varied by >6 log(10), with half maximal effective concentration values in the low pM range against

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