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Pyrazinoic acid amide
Novel small-molecule PGC-1α transcriptional regulator with beneficial effects on diabetic db/db mice
72 hours) inhibits proliferation of multiple cancer cell lines
Chemical Name: 2-amino-5-(3-(piperazin-1-yl)phenyl)-N-(pyridin-4-yl)nicotinamide
Str•mberg K
Wedelolactone 2098 Pyrazinoic acid amideWedelolactone, a natural product from Ecliptae herba, suppresses LPS induced caspase 11 expression by directly inhibiting the IKK Complex[1]. Wedelolactone inhibits 5 lipoxygenase (5 Lox) (IC50~2. 5 M) activity by an oxygen radical scavenging mechanism. Wedelolactone induces caspase dependent apoptosis in prostate cancer cells via downregulation of PKC without inhibiting Akt[2]. Anti cancer, anti inflammatory, and antioxidant activities. Product
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