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HI-TOPK-032 may be further developed as a potential therapeutic against colorectal cancer
CAS Number: 14653-77-1
InChiKey: KYJYDNKATOCUIR-UHFFFAOYSA-N
31-trimethyl-25-(2-methylpropyl)-2
CAS Number: 121058-88-6
PF-5006739 Size:Contact [email protected] for quotation HI-TOPK-032 may be further developedPF 5006739 is a potent and selective inhibitor of CK1 with IC50s of 3. 9 nM and 17. 0 nM, respectively. PF 5006739 is a potential therapeutic agent for a range of psychiatric disorders with low nanomolar in vitro potency for CK1 and high kinome selectivity. PF 5006739 attenuats opioid drug seeking behavior in a rodent operant reinstatement model in animals in a dose dependent manner. PF 5006739 improves glucose tolerance in both diet induced obesity
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