Epothilone B Ala-Ala-Asn-PAB-PNP Smiles: C=CC(=O)N1C/C(=C/C2=CC(=C(F)C=C2)[N+]([O-])=O)/C(=O)/C(/CC1)=C\C1=CC(=C(F)C=C1)[N+]([O-])=O

Smiles: C=CC(=O)N1C/C(=C/C2=CC(=C(F)C=C2)[N+]([O-])=O)/C(=O)/C(/CC1)=C\C1=CC(=C(F)C=C1)[N+]([O-])=O

mTOR kinase

5(10):1049-5

Oral gavage of AT13148 at well-tolerated doses significantly inhibits HGC27 xenograft tumor growth in nude mice

3-dihydro-1H-benzo[d]imidazol-5-yl)-2-methoxybenzamide

Epothilone B Ala-Ala-Asn-PAB-PNP Smiles: C=CC(=O)N1C/C(=C/C2=CC(=C(F)C=C2)[N+]([O-])=O)/C(=O)/C(/CC1)=C\C1=CC(=C(F)C=C1)[N+]([O-])=OEpothilone B is a microtubule stabilizer with a Ki of 0. 71M. It acts by binding to the tubulin heterodimer subunit which causes decreasing of tubulin dissociation. Product information CAS Number: 152044 54 7 Molecular Weight: 507. 68 Formula: C27H41NO6S Synonym: EPO906 EPO 906 EPO 906 EPO 906A EPO B ( ) Epothilone B patupilone Chemical Name: (1S, 3S, 7S, 10R, 11S, 12S, 16R) 7, 11 dihydroxy 8, 8, 10, 12, 16 pentamethyl 3 ((E) 1 (2 methylthiazol 4