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Ro 25-6981 maleate Catalog No.:M9288-2 11aS)-7-hydroxy-9a

SKU: 91630448264

4.0
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Description

11aS)-7-hydroxy-9a

ROC-325 exhibited superior in vitro anticancer effects compared with the existing autophagy inhibitor hydroxychloroquine (HCQ) in 12 different cancer cell lines with diverse genetic backgrounds

LDN193189 or vehicle is applied to mice 5 days post-tumor cell injection before tumors are palpable

Chem-seq permits identification of genomic targets of drugs against androgen receptor regulation selected by functional phenotypic screens

Herndon DN

Ro 25-6981 maleate Catalog No.:M9288-2 11aS)-7-hydroxy-9aRo 25 6981 is a highly potent and selective blocker of N methyl D aspartate receptors containing the NR2B subunit. Ro 25 6981 inhibited 3H MK 801 binding to rat forebrain membranes in a biphasic manner with IC50 values of 0. 003 microM and 149 microM for high (about 60%) and low affinity sites, respectively. NMDA receptor subtypes expressed in Xenopus oocytes were blocked with IC50 values of 0. 009 microM and 52 microM for the subunit combinations

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