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IPA-3 also prevents sphingosine-dependent Pak1 autophosphorylation
InChi: InChI=1S/C10H11NO4/c1-2-3-4-5-10(14)15-11-8(12)6-7-9(11)13/h1H
1-methyl-2-[(E)-2-(thiophen-2-yl)ethenyl]-1
Inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50 = 104 nM) that displays selectivity over enzymes with DPP-like activity (IC50 > 30 μM)
the carboxylic acid is deprotonated (−COO−)
Fmoc-Gln(Trt)-Ser(psi(Me, Me)pro)-OH rosolic acid IPA-3 also prevents sphingosine-dependent Pak1Fmoc Gln(Trt) Ser(psi(Me,Me)pro) OH is a dipeptide. Product information CAS Number: 1821378 64 6 Molecular Weight: 737. 84 Formula: C45H43N3O7 Chemical Name: (4S) 3 [(2S) 2 ({[(9H fluoren 9 yl)methoxy]carbonyl}amino) 4 [(triphenylmethyl)carbamoyl]butanoyl] 2,2 dimethyl 1,3 oxazolidine 4 carboxylic acid Smiles: CC1(C)OC[C@@H](C(O)=O)N1C(=O)[C@H](CCC(=O)NC(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)NC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21 InChiKey: FPGMGQRBDQAVPQ