MA-2029 11194 Smiles: C(C1C=CC=CC=1)N1C(=NN=C1SC1=NC=NC2=C1SC1=NC=CC=C21)C1C=CN=CC=1

Smiles: C(C1C=CC=CC=1)N1C(=NN=C1SC1=NC=NC2=C1SC1=NC=CC=C21)C1C=CN=CC=1

Nemorexant (Compound example 7) is a orexin receptor antagonist with IC50s of 2 nM and 3 nM for Ox1 receptor and Ox2 receptor

4-dimethylphenyl)sulfamoyl]-3H

Formula: C20H13NO5

InChiKey: MWOOGOJBHIARFG-UHFFFAOYSA-N

MA-2029 11194 Smiles: C(C1C=CC=CC=1)N1C(=NN=C1SC1=NC=NC2=C1SC1=NC=CC=C21)C1C=CN=CC=1MA 2029 is a selective, orally active, and competitive motilin receptor antagonist (IC50=4. 9 nM). MA 2029 is selective for the motilin receptor over various other receptors and ion channels. MA 2029 may be useful for gastrointestinal disorders associated with disturbed gastrointestinal motility. Product information CAS Number: 287206 61 5 Molecular Weight: 556. 71 Formula: C31H45FN4O4 Chemical Name: (Z,2S) N [(1S) 2 (3 tert butyl 4 hydroxyphenyl) 1