Fluzoparib (SHR-3162) Size:10 mg solid Chemical Name: 4-(2-((2-(benzo[b]thiophen-3-yl)-9-isopropyl-9H-purin-6-yl)amino)ethyl)phenol

Chemical Name: 4-(2-((2-(benzo[b]thiophen-3-yl)-9-isopropyl-9H-purin-6-yl)amino)ethyl)phenol

Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells

thereby inhibiting endothelial cell-cell interactions

its antitumor effect is similar to that of 5-Fluorouracil

Oral administration of I-BET151 at 10 mg/kg once per day in mice showed efficacy in acute inflammation mouse model

Fluzoparib (SHR-3162) Size:10 mg solid Chemical Name: 4-(2-((2-(benzo[b]thiophen-3-yl)-9-isopropyl-9H-purin-6-yl)amino)ethyl)phenolFluzoparib (SHR3162, HS10160) is a potent Poly (ADP ribose) polymerase (PARP) inhibitor that shows anti tumor activity. Product information CAS Number: 1358715 18 0 Molecular Weight: 472. 40 Formula: C22H16F4N6O2 Chemical Name: 4 (4 fluoro 3 (2 (trifluoromethyl) 5,6,7,8 tetrahydro [1,2,4]triazolo[1,5 a]pyrazine 7 carbonyl)benzyl)phthalazin 1(2H) one Smiles: O=C1NN=C(CC2C=C(C(F)=CC=2)C(=O)N2CC3=NC(=NN3CC2)C(F)(F)F)C2=CC=CC=C12 InChiKey: XJGXCBHXFWBOTN