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Formula: C19H24Cl2N2
InChiKey: FPKARFMSZDBYQF-ILKKLZGPSA-N
Smiles: CC(C)(C)[C@H](NC(=O)COCCOC1=CC=C(C=C1)C1=CC(NC2=CC=C(C=C2)OC(F)(F)F)=NC=N1)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1=CC=C(C=C1)C1SC=NC=1C
Smiles: CNC(=O)O[C@H]1COC2=CC=C(C=C2[C@@H]1NC(=O)C1C=CC(F)=CC=1)N1CCN(CC1)C1COC1
and increased mouse splenic-pLck-pY394 and -IFN-gamma(+) cells in vivo
NVP-LCQ195 oxacillin (sodium monohydrate) Formula: C19H24Cl2N2NVP LCQ195; also known as LCQ 195 and AT9311, is a potent inhibitor of cyclin dependent kinases (CDKs). LCQ195 inhibits CDK1, CDK2 and CDK5, as well as CDK3 and CDK9. LCQ195 induced cell cycle arrest and eventual apoptotic cell death of MM cells, even at sub mol l concentrations, spared non malignant cells, and overcame the protection conferred to MM cells by stroma or cytokines of the bone marrow milieu. Cell cycle regulators, such as cyclin
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