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TCV-309 chloride oanhydroicaritin Smiles: N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CC1C=CC=CC=1)C(O)=O

SKU: 93718104785

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Description

Smiles: N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CC1C=CC=CC=1)C(O)=O

Formula: C37H42F2N8O4

PIK-III binds a unique hydrophobic pocket not present in related kinases such as PI(3)Kα

InChi: InChI=1S/C10H13N5O2/c11-9-8-10(13-4-12-9)15(5-14-8)7-2-1-6(3-16)17-7/h4-7

Chemical Name: 10-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo-1

TCV-309 chloride oanhydroicaritin Smiles: N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CC1C=CC=CC=1)C(O)=OTCV 309 chloride is a potent and specific platelet activating factor (PAF) antagonist. TCV 309 chloride specifically inhibits PAF induced aggregation of rabbit and human platelets, and [3H]PAF binding to rabbit platelet microsomes with IC50 values of 33 nM, 58 nM and 27 nM, respectively. TCV 309 chloride has beneficial effects in anaphylactic shock. Product information CAS Number: 121494 09 5 Molecular Weight: 629. 97 Formula: C30H34BrClN4O4 Chemical

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