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Pixantrone (dimaleate) Catalog No.:M9764-10 Epub 2012 Jul 23

SKU: 9378446662

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Description

Epub 2012 Jul 23

Physiotens hydrochloride

InChi: InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28

with rapid clearance and barely measurable bioavailability

975 μg/mL

Pixantrone (dimaleate) Catalog No.:M9764-10 Epub 2012 Jul 23Pixantrone is a synthetic, noncardiotoxic aza anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Pixantrone is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non Hodgkin lymphoma (aNHL). Product information CAS Number:

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