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O[C@H]1CCCN[C@@H]1CC(=O)CN1C=NC2=CC(Br)=C(Cl)C=C2C1=O
Dactinomycin
) significantly inhibits tumor growth and induced tumor regression in mice bearing LOX tumor xenografts
VEGFR2 and TRK kinases with potential anticancer activity
suggesting that VX-745 can inhibit paracrine multiple myeloma (MM) cell growth in the BM milieu and overcome cell adhesion-related drug resistance
SNS-314 Size:2mg solid O[C@H]1CCCN[C@@H]1CC(=O)CN1C=NC2=CC(Br)=C(Cl)C=C2C1=OSNS 314 is a synthetic small molecule Aurora kinase (AK) inhibitor with potential antineoplastic activity. Aurora kinase inhibitor SNS 314 selectively binds to and inhibits AKs A and B, which may result in the inhibition of cellular division and proliferation in tumor cells that overexpress AKs. AKs are serine threonine kinases that play essential roles in mitotic checkpoint control during mitosis. Product information CAS Number: 1057249 41 8
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