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2 days and 5 days) inhibits growth of U373MG astroeytes
GL0388 shows antiproliferative activities against various cancer cells
Ann Neurol
72 hours) potently inhibit tumorigenic murine macrophage cell line M5076 cellular proliferation
Competitive binding curve of UMI-77 against Mcl-1 is obtained by FP based binding assay using fluorescent labeled Bid BH3 peptide with an IC50 of 1
Nav1.7-IN-2 o-dihydrosphingosine 2 days and 5 days)Nav1. 7 IN 2 is an inhibitor of voltage gated sodium channels (Nav), in particular Nav 1. 7, with IC50 of 80 nM. IC50 value: 80 nMTarget: Nav 1. 7Nav1. 7 IN 2 is useful for the treatment of diseases treatable by inhibition of these channels, in particular, chronic pain disorder. The more detailed information please refer to WO 2011103196 A1. Nav1. 7 IN 2 is a Nav1. 7 channel inhibitor extracted from patent WO 2011103196 A1, compound example J, has an
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