Mc-Val-Cit-PAB-Cl Catalog No.:M25483-C Chemical Name: (S)-N6-propyl-4

Chemical Name: (S)-N6-propyl-4

Chemical Name: 4-methyl-N-[5-methyl-4-(1H-pyrazol-4-yl)-1

Emavusertib

3 days) inhibits the BRAF-mutant human melanoma and colorectal cancer cells proliferation with a EC50 range of 1-10 nM

0 μM Y27632 induced group

Mc-Val-Cit-PAB-Cl Catalog No.:M25483-C Chemical Name: (S)-N6-propyl-4Mc Val Cit PAB Cl is a cleavable ADC linker. Mc Val Cit PAB Cl can be used to conjugate MMAE and antibody to form antibody MC vc MMAE (e. g., anti CD22 MC VC PABC MMAE with IC50s of 3. 3 and 0. 95 nM for BJAB and WSU cell lines in cytotoxicity assay). Product information CAS Number: 1639351 92 0 Molecular Weight: 591. 10 Formula: C28H39ClN6O6 Chemical Name: N [(1S) 1 {[(1S) 4 (carbamoylamino) 1 {[4 (chloromethyl)phenyl]carbamoyl}butyl]carbamoyl} 2