Terfenadine Size:2mg solid 3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13

3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13

25(3):187-95

6 nM and 5

which binds to the kinase with both slow association and dissociation rates

Tsujikawa L

Terfenadine Size:2mg solid 3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13Terfenadine (() Terfenadine) is a potent open channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS dependent apoptosis, simultaneously activates Caspase 4, 2, 9. Product information CAS Number: 50679 08 8 Molecular Weight: 471. 67 Formula: C32H41NO2 Synonym: () Terfenadine MDL 991 Chemical