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2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(morpholinomethyl)-[1
Eigenbrot C
PubMed Central PMCID: PMC4222641
CAS Number: 371942-69-7
thus promoting LRP6 phosphorylation and Wnt signaling transduction
Midostaurin - CAS# 120685-11-2 60268 2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(morpholinomethyl)-[1Midostaurin, CAS No. 120685 11 2, also known as PKC 412, PKC 412A and CGP 41251; is a synthetic indolocarbazole multikinase inhibitor with potential antiangiogenic and antineoplastic activities. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c kit, platelet derived growth factor receptor (PDGFR) and FMS like tyrosine kinase 3 (FLT3) tyrosine kinases, which may result in disruption of the
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