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orally bioavailable and well tolerated pan-Pim kinase inhibitor
KI-7 potentiates the cAMP accumulation induced by the non-selective A2B adenosine receptor agonist NECA (EC50=445
Kanzler SA
13-trioxa-4
211(1):39-51
SHA 68 bamipide orally bioavailable and well toleratedSHA 68 is a potent and selective non peptide neuropeptide S receptor (NPSR) antagonist with IC50s of 22. 0 and 23. 8 nM for NPSR Asn107 and NPSR Ile107, respectively. SHA 68 has limited the blood brain barrier (BBB) penetration and the activity in neuralgia. Product information CAS Number: 847553 89 3 Molecular Weight: 445. 49 Formula: C26H24FN3O3 Chemical Name: (Z) N [(4 fluorophenyl)methyl] 3 oxo 1,1 diphenyl hexahydro 1H [1,3]oxazolo[3,4 a]pyrazine
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