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Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5
(1983) Mol Cell Endocrinol 33: 69-80
TMPA’s binding to Nur77 results in the release and shuttling of LKB1 to the cytoplasm to phosphorylate AMPKα
InChi: InChI=1S/C15H17N3O4S
CUDC-907 also inhibits targets and tumor growth in xenograft tumor models
AMI-1 - Histone Methyltransferase Inhibitor. CAS# 20324-87-2 size:10 mg solid Small-molecule inhibition of MLL activityAMI 1, CAS No. 20324 87 2, is a potent and selective arginine methyltransferase inhibitor, is also a potent scavenger of NADPH oxidase derived superoxide. AMI 1 can modulate nuclear receptor regulated transcription from estrogen and androgen response elements. Product information CAS Number: 20324 87 2 Molecular Weight: 548. 45 Formula: C21H14N2Na2O9S2 Chemical Name: sodium 7,7' (carbonylbis(azanediyl))bis(4 hydroxynaphthalene 2 sulfonate) Smiles:
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