Defiler of Instinct Of all the Defilers, Defiler of Instinct hurts the most from the permanents-only restriction
But Ice Age has a couple of legendary creatures, like General Jarkeld, whose name has been showing up a lot in White and Blue's flavour text
and Delayed Blast Fireball
For example, if the spell is a sorcery, it can only be cast during that player's main phase while the stack is empty
Unless youre interested in running Isamaru, Hound of Konda with extra steps as a commander, best to avoid putting Kytheon, Hero of Akros in your command zone
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