First, dont be afraid to sacrifice your persist creatures to effects like Scarecrone or just use them as blockers
Many viable Rakdos Commanders are available due to a large card pool, each with pros and cons for deck construction
[ Monster Effect ] If this card is sent to the GY or added to your Extra Deck face-up because it was used as Fusion Material: You can choose monsters on the field, up to the number of monsters you control, and place 1 Predator Counter on each one, and if you do, any of those monsters that are Level 2 or higher become Level 1 as long as they have a Predator Counter
Type: Null (Crimson Blaze) is not available in Regular Packs
Plus, its almost free to add to a deck that requires key threats to be protected from spot removal, so your commander gets harder to kill if you have a few untapped creatures laying around
From there work through your deck for some way to either remove your deck with a card like Tainted Pact, or mill yourself with Brain Freeze and win off a Laboratory Maniac