You can run creatures with high toughness without the defender key word and they will be supported by some of your deck but not all of it
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That said, some individual cards that just happen to be knightslike Bloodthirsty Conqueror, Imodane's Recruiter, and Moonshaker Cavalryare among the top-performing knights in competitive play, especially in popular Constructed formats
Those cards are designed around a connected pair of interesting choicesyou creating a choice for your opponent to make
Offering buffs, protection, life gain, and reanimation , Sword of Light and Shadow can be incredibly useful in a great many decks
If that wasnt enough, you can throw in Unnatural Growth to lower the required power to just 30