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Presuming you don't have many other routes to fix your mana, then I'd definitely wait until you can deploy your partially off-color six-drop

If all you are looking to do is turn a Voldaren Epicure into two cards with this I do not think you are doing enough

If that card is an illegal target as the ability tries to resolve, the ability won't resolve and none of its effects will happen

These are a great way to smooth your mana, which is vital when running decks with three colours

It also includes engines that you can slot into your deck to improve its grind or explosiveness

Acid Rain will destroy all Forests, and blue isn't usually known for outright destroying things, even things that belong to enemy colors