FH1 - Hepatocytes Functional Enhancer. CAS# 2719-05-3 090 Smiles: CCCCS(=O)C1SC2=NC(=CC(=C2C=1N)C1C=CC=CC=1)C1=CC=CS1

Smiles: CCCCS(=O)C1SC2=NC(=CC(=C2C=1N)C1C=CC=CC=1)C1=CC=CS1

It displays a high level of selectivity against other members of the PIKK family (IC50 against PI3K isoforms α

Formula: C19H21BrN2O3S

Phase 3 HoFH Lomitapide Study Investigators

PAFc and SEC components from chromatin

FH1 - Hepatocytes Functional Enhancer. CAS# 2719-05-3 090 Smiles: CCCCS(=O)C1SC2=NC(=CC(=C2C=1N)C1C=CC=CC=1)C1=CC=CS1FH1, CAS No. 2719 05 3, is a potent and selective small molecule that enhances hepatocyte functions and promotes the differentiation and maturation of iPSC derived hepatocytes toward a more mature phenotype in vitro. FH1 was identified by a high throughput, cell based screening using primary human hepatocytes. It was added to the basal medium with or without OSM on day 21 after the initiation of differentiation of iPSCs and acted over a period of 9