For example, Lathliss, Dragon Queen and Lozhan, Dragons' Legacy could be your commander, or they could just be one of many payoffs in the 99 of your deck
When someone leaves up 4 mana you should be wary, especially when they have a couple or more cards in hand and so it is very easy to play around
The deck starts by casting a number of wizards with strong secondary abilities including Gandalf the Grey (tap/burn/copy spells), Saruman the White (ward/amass orcs), Gandalf, Friend of the Shire (Sorceries get flash, draw) as well as Siren Stormtamer (counterspell) and Stormchaser Mage (flying/haste/prowess)
$250+ A graded vintage holo
Much like the other cards that make opponents mill half of their deck, Maddening Cacophonys best application is with Bruvac the Grandiloquent, who turns this into a game-winning combo
Not too hard to win from there