It could be through going below zero with a Pact Weapon and then casting Repay In Kind or a Profane Transfusion, or going wide with things like Death's Shadow and Shadow of Mortality
Every pack has at least two
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Synergistic commanders for this creature are Blex, Vexing Pest because of its anthem effect of pumping spiders, among others, and Shelob, Child of Ungoliant, the best spider commander in MTG, because it gives spiders deathtouch and ward 2

Arena Championship 2 March 1819, 2023 Format : Swiss: Phyrexia: All Will Be One Draft + Historic , Top 8: Historic February 2023 Ranked Season The February 2023 Ranked Season begins January 31 at 12:05 PM PT and ends on February 28 at 12 PM PT (UTC-08:00) Bronze Reward : 1 Phyrexia: All Will Be One pack Silver Reward : 1 Phyrexia: All Will Be One pack + 500 gold Gold Reward : 2 Phyrexia: All Will Be One packs + 1,000 gold + Drown in Ichor card style Platinum Reward : 3 Phyrexia: All Will Be One packs + 1,000 gold + Drown in Ichor card style + Skrelv, Defector Mite card style Diamond Reward : 4 Phyrexia: All Will Be One packs + 1,000 gold + Drown in Ichor card style + Skrelv, Defector Mite card style Mythic Reward : 5 Phyrexia: All Will Be One packs + 1,000 gold + Drown in Ichor card style + Skrelv, Defector Mite card style Read the original article from WotC.
Blasphemous Edict is indeed an edict that hits that number 13 trope