This can wipe out most creatures within the first few rounds of play, barring any defensive maneuvers like instant buffs or counterspells
Once there, you can safely tick up those loyalty counters until you choose to either draw a bunch of cards or get a bunch of mana
But white is still the poster child of removal: Wrath of God, Path to Exile, Swords to Plowshares, Banishing Light, Return to Dust and Austere Command all get regular play across formats
When Enduring Tenacity dies, if it was a creature, return it to the battlefield under its owner's control
Heres how Id rate the 10 to start: Tier 1 Archetypes (best decks) UR Big Spells BG Graveyard/Midrange Tier 2 Archetypes (good) Tier 3 Archetypes (decent) UB Control/Good Stuff GW Go Wide/Midrange BR Wizards/Bleeder RG Landfall/Stompy The main delineation between these archetypes is the level of synergy and support they have
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