Opponents are forced to switch their Pokemon, heal up, or risk losing their Pokemon the following turn to a powerful Venoshock from Clodsire ex
Separate all creatures target player controls into two piles
Not only does this synergize well with "edicts" ways to force your opponents to kill their own stuff but Mazirek also capitalizes off of cards that sacrifice themselves such as lands like Evolving Wilds, or Saga enchantments
Rain of Revelation Rain of Revelation is on the expensive side but offers a robust burst of card advantage
Growing Threat Finally, there's a 5% discount on the March of the Machine precon, Growing Threat
It's still a long way away, but the future of this card will be far brighter than the fairly low cost it currently commands, but at least it's a bargain for now