Given Valgavoth's story in Duskmourn, being the enemy of the table at large is an absolute flavor win for the story but it's easy to call something a flavor win when you don't get knocked off the table for running it
The same goes for the cards themselves and how they relate to real-world card-collecting
However, there are some other common ones that I want to mention
Pokmon Trading Card Game Pocket is a digital game, so it cant quite translate all of that, but its trying, and for my money, it comes pretty close
And, because Sagas tend to feature a lot of text and frequently extra abilities, War of the Last AllianceWar of the Last Alliance also has synergy with Frodo, Sauron's BaneFrodo, Sauron's Bane and Frodo, Adventurous HobbitFrodo, Adventurous Hobbit // Sam, Loyal AttendantSam, Loyal Attendant
Of course, you could just cheese the last ability