If Poison Counters arent your thing and they can sometimes be a touchy subject among MTG players Contagion Engines full-throttle double proliferation is still useful in a wide variety of decks
Opposition (Saga/Legacy/Destiny) Now this is everything that Aboshan wasn't: unkillable tapping creatures on a rampage
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Suddenly, Sparksmith killed itself, Pinpoint Avalanche took out your opponent's best creatures instead of your best creature, and that Mythic Proportions your opponent just cast decided to enchant Willbender instead of your opponent's Taunting Elf
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Once Tron has been completed, a common follow up is Wurmcoil Engine or Karn Liberated, both of which most decks arent equipped to deal with on turn three