BI-3802 PyP4 tosylate and oral bioavailability of 32%

and oral bioavailability of 32%

3S)-2-hydroxy-3-[(2S)-2-[(methoxycarbonyl)amino]-3

CAS Number: 175414-77-4

95(4):270-82

EC 690-730-1

BI-3802 PyP4 tosylate and oral bioavailability of 32%BI 3802 is a highly potent BCL6 degrader and inhibits the Bric brac (BTB) domain of BCL6 with an IC50 of 3 nM. BI 3802 induces the polymerization of BCL6 and promotes BCL6 degration depended on E3 ligase SIAH1. BI 3802 has antitumor activity. Product information CAS Number: 2166387 65 9 Molecular Weight: 484. 98 Formula: C24H29ClN6O3 Chemical Name: 2 {[6 ({5 chloro 2 [(3R,5S) 3,5 dimethylpiperidin 1 yl]pyrimidin 4 yl}amino) 1 methyl 2 oxo 1,2