Non-combat related ways to dish out poison counters are also important for any infect strategy and Reaper of Sheoldred, Vraska's Fall, Bloodroot Apothecary, and Venerated Rotpriest do some dirty work
You dont need other effects to deal with Ponders downsides
Additionally, Losheel notably comes along with card draw, allowing you to draw a card once per turn when an artifact creature enters the battlefield under your control for the first time each turn
It wont stop cards such as Deadly Rollick from the same cycle of cards and it cant beat the rare Exterminatus , but it definitely removes much of the risk involved with having a large board state if you havent been able to dedicate mana to holding up interaction
However, as I mentioned before, I wouldn't be surprised to see the EV of Amonkhet increase over the next couple weeks if something in Standard gets banned tomorrow
Each time you use Isochron Scepter to cast Dramatic Reversal, you'll gain one more life than you did the last time