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Silodosin-d4 ac)-PF-06250112 MK-8353 also shows potent antitumor

SKU: 15470150926

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Description

MK-8353 also shows potent antitumor activity against various cancer cell lines

39)29(19)41-31(38)22-13-9-6-10-14-22/h5-14

double-blind

5-Hydroxyindole

Chemical Name: 4-(4-chloro-3-hydroxy-5

Silodosin-d4 ac)-PF-06250112 MK-8353 also shows potent antitumorSilodosin d4 (KAD 3213 d4) is the deuterium labeled Silodosin. Silodosin (KAD 3213) is a potent, selective and orally active 1A adrenergic receptor (1A AR) blocker. Silodosin exhibits high affinity for 1A AR (Ki=0. 036 nM), over 162 fold and 50 fold than for 1B AR and 1D AR with Ki values of 21 nM and 2. 0 nM, respectively. Silodosin is an effective and well tolerated agent, it can be used for the investigation of LUTS BPH. Product information CAS

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